HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-p-cresol → HCID 22732487, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-p-cresol | HCID 17820 | — |
| Reactant | 4-Chloro-2-(2-pyrazinyl)-6-(trifluoromethyl)pyrimidine | HCID 22732367 | — |
| Product | HCID 22732487 | HCID 22732487 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-(2-pyrazinyl)-6-trifluoromethylpyrimidine (40 mg, 0.154 mmol) and 5-hydroxy-2-methylaniline (34 mg, 0.231 mmol) similar to Example 190 and was isolated as a solid (3 mg). 1H NMR (CDCl3): 9.74 (d, J=1.2 Hz, 1H), 8.76-8.71 (m, 2H), 7.30 (brs, 1H), 7.18 (d, J=8.4 Hz, 1H), 6.87 (brd, 1H), 6.78 (dd, J=8.4, 2.4 Hz, 1H), 6.73 (s, 1H), 2.21 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716851B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-5c6a9c095c504170b9e8211c4d558165 |
| Source note | uspto-grants-2004_04 |