HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethoxypyridin-3-amine → HCID 22732430, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethoxypyridin-3-amine | HCID 593005 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 22732430 | HCID 22732430 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-trifluoromethylpyrimidine (50 mg, 0.192 mmol) and 3-amino-2,6-dimethoxypyridine (44 mg, 0.288 mmol) similar to Example 180 and was isolated as a yellow solid (15 mg, 20%). 1H NMR (CDCl3): 9.62 (brs, 1H), 8.72-8.67 (m, 2H), 7.42 (dd, J=8.1, 5.4 Hz, 1H), 7.09 (s, 1H), 6.75 (s, 1H), 6.43 (d, J=8.7 Hz, 1H), 4.08 (s, 3H), 4.02 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716851B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-d5ba6ad1daff4ecd9cb5ee42383b02a1 |
| Source note | uspto-grants-2004_04 |