HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine → HCID 22732476, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Reactant | 5-Chloro-2-methylpyrimidin-4-amine | HCID 22732409 | — |
| Product | HCID 22732476 | HCID 22732476 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-trifluoromethylpyrimidine (50 mg, 0.192 mmol) and 4-amino-5-chloro-2-methylpyrimidine (42 mg, 0.288 mmol) similar to Example 190 and was isolated as a solid. 1H NMR (CDCl3): 9.58 (d, J=1.5 Hz, 1H), 8.72-8.65 (m, 2H), 7.42 (dd, J=6, 5.1 Hz, 1H), 6.70 (s, 1H), 5.32 (s, 2H), 1.70 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716851B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-8ab571b13a154a0096cd0af43e20f070 |
| Source note | uspto-grants-2004_04 |