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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084253Generated: October 30, 2026

4-Amino-1,2,4-triazole → HCID 22732461, compound

https://huagongshe.com/reaction/2084253

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-1,2,4-triazoleHCID 11432—
Reactant4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidineHCID 1485990—
ProductHCID 22732461HCID 22732461—

Reaction Steps

The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-trifluoromethylpyrimidine (50 mg, 0.192 mmol) and 1-amino-1,3,4-triazole (24 mg, 0.288 mmol) similar to Example 190 and was isolated as a solid. 1H NMR (CDCl3): 9.61 (brs, 1H), 8.71-8.66 (m, 4H), 7.41 (m, 2H), 6.69 (s, 1H), 5.18 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716851B2
Source datasetuspto-grants-2004_04
ORD IDord-83d42747eb004ae58677ab314766daa9
Source noteuspto-grants-2004_04