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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084258Generated: October 25, 2026

3-(Trifluoromethyl)benzoyl chloride → N'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide

https://huagongshe.com/reaction/2084258

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzoyl chlorideHCID 75257—
Reactant2-PhenoxynicotinohydrazideHCID 2797685—
SolventPyridineHCID 1049—
ProductN'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazideHCID 2797700—

Reaction Steps

Alternatively, as shown in scheme 2, reaction of 2-phenoxy-nicotinic acid hydrazide with 3-trifluoromethyl-benzoyl chloride in the presence of a base such as pyridine produced N′-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide as the product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716859B2
Source datasetuspto-grants-2004_04
ORD IDord-1bf87609dea646c894905922e97c9cf7
Source noteuspto-grants-2004_04