3-(Trifluoromethyl)benzaldehyde → HCID 86587162, compound

HRID 2084266Notes

Reaction equation

HRID 2084266 reaction equation
[F:1][C:2]([F:21])([F:20])[C:3]1[CH:4]=[C:5]([NH:9][C:10]2[N:19]=[CH:18][CH:17]=[CH:16][C:11]=2[C:12]([NH:14][NH2:15])=[O:13])[CH:6]=[CH:7][CH:8]=1.[F:22][C:23]([F:33])([F:32])[C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=1)[CH:27]=O>>[F:22][C:23]([F:32])([F:33])[C:24]1[CH:25]=[C:26]([CH:29]=[CH:30][CH:31]=1)[CH:27]=[N:15][NH:14][C:12]([C:11]1[C:10]([NH:9][C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:20])([F:1])[F:21])[CH:4]=2)=[N:19][CH:18]=[CH:17][CH:16]=1)=[O:13]

Participants

3

Reactant 2

HCID 679903-(Trifluoromethyl)benzaldehydeHCID 15039188HCID 15039188, compound

Product 1

HCID 86587162HCID 86587162, compound

Procedure

The title compound was prepared from 2-(3-trifluoromethyl-phenylamino)-nicotinic acid-hydrazide and 3-trifluoromethyl-benzaldehyde by a procedure similar to Example 22. 1H NMR (DMSO-d6): 12.30 (s, 1H), 10.58 (s, 1H), 8.53 (s, 1H), 8.45 (d, J=4.5 Hz, 1H), 8.31 (s, 1H), 8.24 (d, J=8.1 Hz, 1H), 8.12 (s, 1H), 8.06 (d, J=8.1 Hz), 7.84 (m, 3H), 7.54 (t, J=8.1 Hz, 1H), 7.30 (d, J=8.1 Hz, 1H), 7.03 (q, J=4.5 Hz, 1H).

Sources & evidence

ORD record
ord-dffd8e2199ea4f2fbe20ea92d2bed16f
Source dataset
uspto-grants-2004_04
Patent number
US06716859B2

Reaction notes

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