3-(Trifluoromethyl)benzaldehyde → HCID 86587166, compound

HRID 2084279Notes

Reaction equation

HRID 2084279 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([N:8]2[CH:12]=[N:11][C:10]([CH2:13][O:14][C:15]3[CH:24]=[CH:23][CH:22]=[CH:21][C:16]=3[C:17]([NH:19][NH2:20])=[O:18])=[N:9]2)[CH:5]=[CH:4][CH:3]=1.[F:25][C:26]([F:36])([F:35])[C:27]1[CH:28]=[C:29]([CH:32]=[CH:33][CH:34]=1)[CH:30]=O>>[F:25][C:26]([F:35])([F:36])[C:27]1[CH:28]=[C:29]([CH:32]=[CH:33][CH:34]=1)[CH:30]=[N:20][NH:19][C:17](=[O:18])[C:16]1[CH:21]=[CH:22][CH:23]=[CH:24][C:15]=1[O:14][CH2:13][C:10]1[N:11]=[CH:12][N:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([Cl:1])[N:7]=2)[N:9]=1

Participants

3

Reactant 2

HCID 679903-(Trifluoromethyl)benzaldehydeHCID 1478571HCID 1478571, compound

Product 1

HCID 86587166HCID 86587166, compound

Procedure

The title compound was prepared from 2-[1-(6-chloro-pyridin-2-yl)-1H-[1,2,4]triazol-3-ylmethoxy]-benzoic acid hydrazide and 3-trifluoromethyl-benzaldehyde by a procedure similar to Example 22. 1H NMR (DMSO-d6): 11.92 (s, 1H), 8.43 (s, 1H), 8.0 (m, 3H), 7.80 (m, 3H), 7.70 (t, J=7.5 Hz, 1H), 7.60 (m, J=7.5 Hz, 1H), 7.45 (d, J=8.4 Hz, 1H), 7.17 (d, J=7.5 Hz, 1H), 5.50 (s, 1H).

Sources & evidence

ORD record
ord-e1dc86ec07e34a45861d8502c43ef0cf
Source dataset
uspto-grants-2004_04
Patent number
US06716859B2

Reaction notes

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