HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[3-(3-benzyloxyphenyl)propyl]-1H-1,2,3-triazole → 3-[3-(1H-1,2,3-Triazole-1-yl)propyl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[3-(3-benzyloxyphenyl)propyl]-1H-1,2,3-triazole | HCID 12109870 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-[3-(1H-1,2,3-Triazole-1-yl)propyl]phenol | HCID 12109869 | 91.4% |
Reaction Steps
To a solution of 1-[3-(3-benzyloxyphenyl)propyl]-1H-1,2,3-triazole (0.937 g) in methanol (32 ml), 10% palladium carbon (0.1 g) was added, followed by vigorous stirring in a hydrogen atmosphere at room temperature for 8 hours. The catalyst was filtered off; the filtrate was concentrated to dryness under reduced pressure to yield the titled compound (0.593 g) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716863B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-22120966e2a9439a849a5a9e45fcedc2 |
| Source note | uspto-grants-2004_04 |