(2R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acid → HCID 60077664, compound

HRID 2084454Notes

Reaction equation

HRID 2084454 reaction equation
[C:1]([O:5][C:6](=[O:21])[CH2:7][C@@H:8]([CH2:12][CH2:13][CH2:14][CH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1)[C:9]([OH:11])=[O:10])([CH3:4])([CH3:3])[CH3:2].[CH:22]([N:35]1[CH2:38][CH:37]([C:39](=[N:41]O)[NH2:40])[CH2:36]1)([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[NH2:41]/[C:39](=[N:40]\[O:10][C:9]([C@H:8]([CH2:12][CH2:13][CH2:14][CH:15]1[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]1)[CH2:7][C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:21])=[O:11])/[CH:37]1[CH2:38][N:35]([CH:22]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH2:36]1

Participants

3

Reactant 2

HCID 9835906(2R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acidHCID 73768728HCID 73768728, compound

Product 1

HCID 60077664HCID 60077664, compound

Procedure

Method as for preparation 2 using (2R)-2-(2-tert-butoxy-2-oxoethyl)-5-cyclohexylpentanoic acid (1.65 g, 5.51 mmol) and 1-benzhydryl-N′-hydroxy-3-azetidinecarboximidamide (preparation 34) (1.74 g, 6.17 mmol) as starting materials.

Sources & evidence

ORD record
ord-13fdb9de6aae4bf88d7e7edf58d4632d
Source dataset
uspto-grants-2004_04
Patent number
US06716861B2

Reaction notes

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