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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084461Generated: November 1, 2026

Cyclopropanecarbonyl chloride → HCID 60077593, compound

https://huagongshe.com/reaction/2084461

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbonyl chlorideHCID 77637—
Reactanttert-butyl(3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoateHCID 16747946—
ProductHCID 60077593HCID 60077593107.5%

Reaction Steps

Method as for preparation 50 using tert-butyl (3R)-3-[3-(aminomethyl)-1,2,4-oxadiazol-5-yl]-6-cyclohexylhexanoate (preparation 18) (204 mg, 0.57 mmol) and cyclopropane carboxylic acid chloride (62 μl, 0.68 mmol) as starting materials to afford the title compound as a colourless oil (257 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716861B2
Source datasetuspto-grants-2004_04
ORD IDord-69d9744a5ce645ddb6561ea8d929273b
Source noteuspto-grants-2004_04