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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084471Generated: October 30, 2026

Isopropylamine → tert-butyl(3R)-6-cyclohexyl-3-{3-[(isopropylamino)methyl]-1,2,4-oxadiazol-5-yl}hexanoate

https://huagongshe.com/reaction/2084471

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
Reactanttert-Butyl (3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)1,2,4-oxadiazol-5-yl]hexanoateHCID 16747945—
Producttert-butyl(3R)-6-cyclohexyl-3-{3-[(isopropylamino)methyl]-1,2,4-oxadiazol-5-yl}hexanoateHCID 16748070—

Reaction Steps

Method as for preparation 5 using tert-butyl (3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)-1,2,4-oxadiazol-5-yl]hexanoate (preparation 177) (490 mg, 0.97 mmol) and isopropylamine (175 mg, 3.00 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716861B2
Source datasetuspto-grants-2004_04
ORD IDord-e7a4ab4164e94b1fb0a0925fd58ca9ad
Source noteuspto-grants-2004_04