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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084472Generated: October 30, 2026

Tert-Butylamine → tert-butyl(3R)-3-{3-[(tert-butylamino)methyl]-1,2,4-oxadiazol-5-yl}-6-cyclohexylhexanoate

https://huagongshe.com/reaction/2084472

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
Reactanttert-Butyl (3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)1,2,4-oxadiazol-5-yl]hexanoateHCID 16747945—
Producttert-butyl(3R)-3-{3-[(tert-butylamino)methyl]-1,2,4-oxadiazol-5-yl}-6-cyclohexylhexanoateHCID 16748071—

Reaction Steps

Method as for preparation 5 using tert-butyl (3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)-1,2,4-oxadiazol-5-yl]hexanoate (preparation 177) (500 mg, 0.99 mmol) and tert-butylamine (216 mg, 2.96 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716861B2
Source datasetuspto-grants-2004_04
ORD IDord-fb9b058771964cd2a3b7392bc7c4d2be
Source noteuspto-grants-2004_04