2-[2-(Tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acid → HCID 16749200, compound

HRID 2084494Notes

Reaction equation

HRID 2084494 reaction equation
[C:1]([O:5][C:6](=[O:21])[CH2:7][CH:8]([CH2:12][CH2:13][CH2:14][CH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1)[C:9]([OH:11])=O)([CH3:4])([CH3:3])[CH3:2].O[NH:23][C:24](=[NH:32])[CH2:25][N:26]1[CH2:31][CH2:30][O:29][CH2:28][CH2:27]1>>[CH:15]1([CH2:14][CH2:13][CH2:12][C@@H:8]([C:9]2[O:11][N:32]=[C:24]([CH2:25][N:26]3[CH2:31][CH2:30][O:29][CH2:28][CH2:27]3)[N:23]=2)[CH2:7][C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:21])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 213050372-[2-(Tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acidHCID 178511318HCID 178511318, compound

Product 1

HCID 16749200HCID 16749200, compound

Procedure

Method as for preparations 2 and 3 combined using 2-[2-(tert-butoxy)-2-oxoethyl]-5-cyclohexylpentanoic acid (preparation 168) (1.00 g, 3.36 mmol) and N-hydroxy-2-(4-morpholinyl)ethanimidamide (J. Org. Chem.; 1958, 23, 1112) (534 mg, 3.36 mmol) as starting material.

Sources & evidence

ORD record
ord-a0d9217ea6c544babb9c8feab99f9e73
Source dataset
uspto-grants-2004_04
Patent number
US06716861B2

Reaction notes

Loading…