HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylamine → (3R)-N-(benzyloxy)-6-cyclohexyl-3-{4-[(cyclopentylamino)methyl]-1,3-oxazol-2-yl}hexanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylamine | HCID 2906 | — |
| Reactant | (3R)-N-(benzyloxy)-6-cyclohexyl-3-(4-formyl-1,3-oxazol-2-yl)hexanamide | HCID 60077589 | — |
| Product | (3R)-N-(benzyloxy)-6-cyclohexyl-3-{4-[(cyclopentylamino)methyl]-1,3-oxazol-2-yl}hexanamide | HCID 60077641 | 52.2% |
Reaction Steps
Method and purification as for preparation 157 using (3R)-N-(benzyloxy)-6-cyclohexyl-3-(4-formyl-1,3-oxazol-2-yl)hexanamide (preparation 156) (200 mg, 0.50 mmol) and cyclopentylamine (50 μl, 0.50 mmol) as starting materials to afford the title compound as a colourless oil (122 mg, 48%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716861B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-7ec4682249fb449c88d0db35bb2073d1 |
| Source note | uspto-grants-2004_04 |