2-Furoyl isothiocyanate → HCID 22397379, compound

HRID 2084672Notes

Reaction equation

HRID 2084672 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]=[C:9]=[S:10])=[O:7].[NH2:11][CH2:12][CH2:13][CH2:14][N:15]1[C:23]2[C:22]([CH3:24])=[C:21]([CH3:25])[N:20]=[C:19]([NH2:26])[C:18]=2[N:17]=[C:16]1[CH2:27][O:28][CH2:29][CH3:30]>>[NH2:26][C:19]1[C:18]2[N:17]=[C:16]([CH2:27][O:28][CH2:29][CH3:30])[N:15]([CH2:14][CH2:13][CH2:12][NH:11][C:9]([NH:8][C:6]([C:2]3[O:1][CH:5]=[CH:4][CH:3]=3)=[O:7])=[S:10])[C:23]=2[C:22]([CH3:24])=[C:21]([CH3:25])[N:20]=1

Participants

3

Reactant 2

HCID 27592432-Furoyl isothiocyanateHCID 219738361-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine

Product 1

HCID 22397379HCID 22397379, compound

Procedure

Using the method of Examples 94-105, 2-furoylisothiocyanate was reacted with 1-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 431.1846.

Sources & evidence

ORD record
ord-74498dec93b94dada22dee3fc70411a1
Source dataset
uspto-grants-2004_04
Patent number
US06716988B2

Reaction notes

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