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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084677Generated: October 26, 2026

Phosphorisocyanatidic acid, diethyl ester → diethyl{[2-(4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)ethyl]amino}carbonylamidophosphate

https://huagongshe.com/reaction/2084677

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorisocyanatidic acid, diethyl esterHCID 580184—
Reactant1-(2-aminoethyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amineHCID 21973820—
Productdiethyl{[2-(4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)ethyl]amino}carbonylamidophosphateHCID 22397376—

Reaction Steps

Using the method of Examples 118-133, diethoxyphosphinyl isocyanate was reacted with 1-(2-aminoethyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 399.1926.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716988B2
Source datasetuspto-grants-2004_04
ORD IDord-a2cf05397b2c4b379b4c4f5770ec1fa6
Source noteuspto-grants-2004_04