Mesitylene → HCID 22734545, compound

HRID 2084686Notes

Reaction equation

HRID 2084686 reaction equation
C([O:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[CH:7]=[CH:8][N:9]2[S:14]([C:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=1)(=[O:16])=[O:15])C=C.[C:24]1(C)[CH:29]=C(C)C=C(C)[CH:25]=1>>[CH2:29]([C:13]1[CH:12]=[CH:11][C:10]2[N:9]([S:14]([C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=3)(=[O:15])=[O:16])[CH:8]=[CH:7][C:6]=2[C:5]=1[OH:4])[CH:24]=[CH2:25]

Participants

3

Reactant 2

HCID 7947MesityleneHCID 22734530HCID 22734530, compound

Product 1

HCID 22734545HCID 22734545, compound

Procedure

Refluxing a solution of 4-(allyloxy)-1-[(4-methylphenyl)sulfonyl]-1H-indole in mesitylene followed by removal of the solvent and subsequent purification by flash column chromatography provides 5-allyl-1-[(4-methylphenyl)sulfonyl]-1H-indol-4-ol.

Workup

  1. customfollowed by removal of the solvent and subsequent purification by flash column chromatography

Sources & evidence

ORD record
ord-1b445252f5c544a6973c1fd7b9e6c4fe
Source dataset
uspto-grants-2004_04
Patent number
US06716998B2

Reaction notes

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