HCID 86588271, compound → HCID 86588273, compound

HRID 2084688Notes

Reaction equation

HRID 2084688 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([O:11][CH2:12][C@@H:13]2[O:35][C:17]3=[C:18]4[C:22](=[CH:23][CH:24]=[C:16]3[CH:15]=[CH:14]2)[N:21]([S:25]([C:28]2[CH:33]=[CH:32][C:31]([CH3:34])=[CH:30][CH:29]=2)(=[O:27])=[O:26])[CH:20]=[CH:19]4)(=[O:10])=[O:9])=[CH:4][CH:3]=1>[Pd].C(O)C>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([O:11][CH2:12][C@@H:13]2[O:35][C:17]3=[C:18]4[C:22](=[CH:23][CH:24]=[C:16]3[CH2:15][CH2:14]2)[N:21]([S:25]([C:28]2[CH:29]=[CH:30][C:31]([CH3:34])=[CH:32][CH:33]=2)(=[O:26])=[O:27])[CH:20]=[CH:19]4)(=[O:9])=[O:10])=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 86588271HCID 86588271, compound

Product 1

HCID 86588273HCID 86588273, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Treatment of {(2R)-7-[(4-methylphenyl)sulfonyl]-2,7-dihydropyrano[2,3-e]indol-2-yl}methyl 4-methylbenzenesulfonate with palladium on carbon (10 wt. %) in ethanol following the procedure described for Example 1c gives {(2R)-7-[(4-methylphenyl)sulfonyl]-2,3,4,7-tetrahydropyrano[2,3-e]indol-2-yl}methyl 4-methylbenzenesulfonate.

Sources & evidence

ORD record
ord-e225478a0c3c45fd8bd707808813a235
Source dataset
uspto-grants-2004_04
Patent number
US06716998B2

Reaction notes

Loading…