反应详情

温度

24 °C

4-Chloroacetoacetyl chloride (35% strength solution in dichloromethane, 26.2 g, 59 mmol), mesitylene (7.4 g, 59 mmol, and scandium trifluoro-methanesulphonate (2.6 g, 5.1 mmol) were introduced at 20° C. The reaction mixture was then stirred at 24° C. for a total of 2 days. It was then hydrolysed with water (10 ml). The organic phase was concentrated, and the residue was dried in a high vacuum. 9.1 g of crude product were obtained.

1. concentrationThe organic phase was concentrated
2. customthe residue was dried in a high vacuum