HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylcatechol → 4-Methyl-1,3-benzodioxole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylcatechol | HCID 340 | — |
| Reactant | Dibromomethane | HCID 3024 | — |
| Catalyst | Trioctylmethylammonium chloride | HCID 21218 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Methyl-1,3-benzodioxole | HCID 88560 | — |
Reaction Steps
11.6 g Adogen 464 and 7 mL of dibromomethane were refluxed in 50 mL of H2O for 0.5 hours under argon. 3-Methylcatechol (8.89 g, 71.6 mmol) was added over 2 hours and the mixture refluxed for an additional 1 hour. Distillation of the product from the reaction mixture afforded the title compound as a yellow oil: HRMS m/e 136.0524 (calc'd for C8H8O2, 136.0524).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716991B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-1166a49e4f1344479ca9f38c6f13f55f |
| Source note | uspto-grants-2004_04 |