HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneacetic acid, 2-fluoro- → HCID 10728612, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneacetic acid, 2-fluoro- | HCID 67979 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Magnesium Chloride | HCID 5360315 | — |
| Reactant | HCID 23679020 | HCID 23679020 | — |
| Product | HCID 10728612 | HCID 10728612 | — |
Reaction Steps
That is, 2-fluorophenylacetic acid (4) and 1,1′-carbonyldiimidazole (CDI) are reacted, followed by treatment with ethyl methylmalonate mono potassium salt in the presence of magnesium chloride to obtain ethyl 4-(2-fluorophenyl)-2-methyl-3-oxobutyrate (5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06717016B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-fc00ac4136334554abc7861439ebf569 |
| Source note | uspto-grants-2004_04 |