HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10728612, compound → HCID 12070572, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10728612 | HCID 10728612 | — |
| Reactant | 4,4'-Bi-1,3-benzodioxole-5,5'-diylbis(diphenylphosphine) | HCID 11017510 | — |
| Product | HCID 12070572 | HCID 12070572 | — |
Reaction Steps
The thus obtained compound (5) is asymmetrically hydrogenated using ((R)—SEGPHOS™)-Ru complex to obtain optically active ethyl 4-(2-fluorophenyl)-3-hydroxy-2-methylbutyrate (6) as a mixture of diastereomers.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06717016B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-084af2cc9280444c8e18d6d8f3470fc4 |
| Source note | uspto-grants-2004_04 |