Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084754Generated: October 25, 2026

3-Aminopyridine → (+/-)-4-[(3,5-Dichloro-4-pyridyl)aminocarbonyl]-7-methoxy-3-[(3-pyridyl)aminocarbonyl]methyl-2,3-dihydro-benzofuran

https://huagongshe.com/reaction/2084754

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-AminopyridineHCID 10009—
Reactant(+/-)-3-Carboxymethyl-4-(3,5-dichloro-4-pyridylamino-carbonyl)-7-methoxy-2,3-dihydrobenzofuranHCID 22734342—
Product(+/-)-4-[(3,5-Dichloro-4-pyridyl)aminocarbonyl]-7-methoxy-3-[(3-pyridyl)aminocarbonyl]methyl-2,3-dihydro-benzofuranHCID 2273397251%

Reaction Steps

Substantially the same procedure as in Example 13 was repeated using Compound 9 (0.30 g) obtained in Example 9 and 3-aminopyridine to give Compound 19 (0.18 g, 51%) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716987B1
Source datasetuspto-grants-2004_04
ORD IDord-ff02a0ff34bd4c0aa259c5733513bbf6
Source noteuspto-grants-2004_04