HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylpropylamine → N-(3-phenylpropyl)-7-methoxybenzofuran-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylpropylamine | HCID 16259 | — |
| Reactant | 7-Methoxy-1-benzofuran-2-carboxylic acid | HCID 606037 | — |
| Product | N-(3-phenylpropyl)-7-methoxybenzofuran-2-carboxamide | HCID 22734240 | — |
Reaction Steps
Substantially the same procedure as in Example 219 was repeated using a starting material, 7-methoxybenzofuran-2-carboxylic acid, and 3-phenylpropylamine to give N-(3-phenylpropyl)-7-methoxybenzofuran-2-carboxamide (Compound 239a). Successively, it was formylated to give N-(3-phenylpropyl)-4-formyl-7-methoxybenzofuran-2-carboxamide (Compound 239b), then compound 239b was reacted with cyclobutylamine to give compound 239 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716987B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-c276b7224d3347b4869d5cda80233d8d |
| Source note | uspto-grants-2004_04 |