HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 2-Phenylaminocarbonyl-7-methoxybenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 7-Methoxy-1-benzofuran-2-carboxylic acid | HCID 606037 | — |
| Product | 2-Phenylaminocarbonyl-7-methoxybenzofuran | HCID 22734071 | — |
Reaction Steps
Substantially the same procedure as in Example 219 was repeated using a starting material, 7-methoxybenzofuran-2-carboxylic acid, and aniline to give N-phenyl-7-methoxybenzofuran-2-carboxamide (Compound 249a). Successively, it was formylated to give N-phenyl-4-formyl-7-methoxybenzofuran-2-carboxamide (Compound 249b), then compound 249b was reacted with methylamine hydrochloride to give compound 249 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716987B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-a3ef85b286d545299efc6677d19b39e4 |
| Source note | uspto-grants-2004_04 |