HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Tert-Butylaniline → N-(4-t-butylphenyl)-7-methoxybenzofuran-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Tert-Butylaniline | HCID 69861 | — |
| Reactant | 7-Methoxy-1-benzofuran-2-carboxylic acid | HCID 606037 | — |
| Product | N-(4-t-butylphenyl)-7-methoxybenzofuran-2-carboxamide | HCID 22734191 | — |
Reaction Steps
Substantially the same procedure as in Example 219 was repeated using a starting material, 7-methoxybenzofuran-2-carboxylic acid, and 4-t-butylaniline to give N-(4-t-butylphenyl)-7-methoxybenzofuran-2-carboxamide (Compound 389a). Successively, it was formylated to give N-(4-t-butylphenyl)-4-formyl-7-methoxybenzofuran-2-carboxamide (Compound 389b), then compound 389b was reacted with cyclobutylamine to give compound 389 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716987B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-257f5c8e8c034d7889cd7b3dfc88d096 |
| Source note | uspto-grants-2004_04 |