HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Butyne-1,4-diol → HCID 21304721, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Butyne-1,4-diol | HCID 8066 | — |
| Reactant | HCID 57020974 | HCID 57020974 | — |
| Product | HCID 21304721 | HCID 21304721 | 65.2% |
Reaction Steps
According to the procedure of Step 2 of Example 248, Mitsunobu coupling of 0.10 g (0.288 mmoL) of methyl(3S)-4-[(4-hydroxyphenyl)sulfonyl]-2,2-dimethyl-3-thiomorpholinecarboxylate and 0.031 g (0.363 mmol) of 2-butyne-1,4-diol gave 0.078 g of methyl(3S)-4-({4-[(4-hydroxy-2-butynyl)oxy]phenyl}sulfonyl)-2,2-dimethyl-3-thiomorpholine carboxylate as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716833B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-3a5117b507ea4e29a0db9c074145c8b9 |
| Source note | uspto-grants-2004_04 |