HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyl iodide → Ethyl 4-benzyloxy-1-(2-methylpropyl)indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyl iodide | HCID 10556 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Ethyl 4-(phenylmethoxy)-1H-indole-2-carboxylate | HCID 119707 | — |
| Product | Ethyl 4-benzyloxy-1-(2-methylpropyl)indole-2-carboxylate | HCID 22729270 | — |
Reaction Steps
By the reactions in the same manner as in Starting Material Synthesis Example 9 using ethyl 4-benzyloxy-1H-indole-2-carboxylate (10.0 g), sodium hydride (1.6 g) and isobutyl iodide (3.3 ml), the title compound (6.0 g) was obtained as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720320B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-8a2fbc9921494880befd67ee21a19c9c |
| Source note | uspto-grants-2004_04 |