(S)-(+)-Glycidyl-4-nitrobenzoate → HCID 60078047, compound

HRID 2085159Notes

Reaction equation

HRID 2085159 reaction equation
[OH:1][C:2]1[C:7]2[O:8][C:9]([C:11]3[O:12][C:13]([C:16]([F:19])([F:18])[F:17])=[N:14][N:15]=3)=[CH:10][C:6]=2[CH:5]=[CH:4][CH:3]=1.S(C1C=CC([N+]([O-])=O)=CC=1)(O[CH2:24][C@H:25]1[O:27][CH2:26]1)(=O)=O>>[CH2:24]([O:1][C:2]1[C:7]2[O:8][C:9]([C:11]3[O:12][C:13]([C:16]([F:19])([F:18])[F:17])=[N:14][N:15]=3)=[CH:10][C:6]=2[CH:5]=[CH:4][CH:3]=1)[C@H:25]1[O:27][CH2:26]1

Participants

3

Reactant 2

HCID 10868995(S)-(+)-Glycidyl-4-nitrobenzoateHCID 22729309HCID 22729309, compound

Product 1

HCID 60078047HCID 60078047, compoundYield 36.1%

Procedure

By the reactions in the same manner as in Starting Material Synthesis Example 1 using 2-(7-hydroxybenzo(b)furan-2-yl)-5-trifluoromethyl-1,3,4-oxadiazole (2.4 g) and (S)-glycidyl nosylate (2.2 g), the title compound (1.0 g) was obtained as white crystals.

Sources & evidence

ORD record
ord-97e2f7ff56d54008a0d09ba4f928a28b
Source dataset
uspto-grants-2004_04
Patent number
US06720320B2

Reaction notes

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