HuagongsheHuagongshe Chemistry Print Report · For research reference only
trans-2-Phenyl-1-cyclopropanecarbonyl chloride → 2-(ethoxymethyl)-6,7-dimethyl-1-[2-(1-{[(1R*,2R*)-2-phenylcyclopropyl]carbonyl}piperidin-4-yl)ethyl]-1H-imidazo[4,5-c]pyridin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | trans-2-Phenyl-1-cyclopropanecarbonyl chloride | HCID 13656 | — |
| Reactant | 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine | HCID 12972962 | — |
| Product | 2-(ethoxymethyl)-6,7-dimethyl-1-[2-(1-{[(1R*,2R*)-2-phenylcyclopropyl]carbonyl}piperidin-4-yl)ethyl]-1H-imidazo[4,5-c]pyridin-4-amine | HCID 20575807 | — |
Reaction Steps
Using the method of Examples 61-75, trans-2-phenyl-1-cyclopropanecarbonyl chloride was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired product. The observed accurate mass was 476.3039.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720333B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-e2bb503e3ad44b20a17cb451e19b78a1 |
| Source note | uspto-grants-2004_04 |