2-Furoyl isothiocyanate → HCID 22397378, compound

HRID 2085319Notes

Reaction equation

HRID 2085319 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]=[C:9]=[S:10])=[O:7].[NH2:11][CH2:12][CH2:13][CH2:14][N:15]1[C:23]2[C:22]([CH3:24])=[C:21]([CH3:25])[N:20]=[C:19]([NH2:26])[C:18]=2[N:17]=[C:16]1[CH3:27]>>[NH2:26][C:19]1[C:18]2[N:17]=[C:16]([CH3:27])[N:15]([CH2:14][CH2:13][CH2:12][NH:11][C:9]([NH:8][C:6]([C:2]3[O:1][CH:5]=[CH:4][CH:3]=3)=[O:7])=[S:10])[C:23]=2[C:22]([CH3:24])=[C:21]([CH3:25])[N:20]=1

Participants

3

Reactant 2

HCID 27592432-Furoyl isothiocyanateHCID 219460311-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine

Product 1

HCID 22397378HCID 22397378, compound

Procedure

Using the methods of Examples 75-85, 2-furoylisothiocyanate was reacted with 1-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 387.1608.

Sources & evidence

ORD record
ord-76eaac4bf1f843b08e3202b95e4af089
Source dataset
uspto-grants-2004_04
Patent number
US06720334B2

Reaction notes

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