Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Acetoacetate → 1-(3,4-Dimethylphenyl)-3-methyl-3-pyrazolin-5-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | 1-(3,4-Dimethylphenyl)hydrazine | HCID 173741 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 1-(3,4-Dimethylphenyl)-3-methyl-3-pyrazolin-5-one | HCID 11735829 | 156.7% |
반응 단계
A solution of 3,4-dimethylphenylhydrazine (7.3 g; 0.053 mol.) and ethyl acetoacetate (6.9 g; 0.053 mol.) in glacial acetic acid (50.0 mL) was stirred and heated at 100° for 24 h. The solvent was evaporated and the product purified by chromatography (silica gel, 50% ethyl acetate/hexanes) to afford the title compound (16.8 g; 64%). MS(ES) m/z 203 [M+H].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06720345B1 |
| 출처 데이터셋 | uspto-grants-2004_04 |
| ORD ID | ord-10e7b5e7ebe84c43a488d0cfbc89fb57 |
| 출처 메모 | uspto-grants-2004_04 |