Pentane → 3,3-Dimethyl-7-iso-propyl-2,3-dihydro-benzofuran-5-boronic acid

Participants

Reaction Steps

Following General Procedure A and using 5-bromo-3,3-dimethyl-7-iso-propyl-2,3-dihydro-benzofuran (0.8 g, 3 mmol), 15 mL of anhydrous tetrahydrofuran, 1.7M solution of t-butyllithium in n-pentane (3.53 mL, 6 mmol) and trimethyl borate (0.75 mL, 6 mmol), the title compound was obtained as a foam that was used as such for the next step without purification and characterization. 5-Bromo-3,3-dimethyl-7-iso-propyl-2,3-dihydro-benzofuran can be prepared as described in U.S. Pat. No. 6,093,838.

Provenance & Evidence