HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 22731342, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 22731282 | HCID 22731282 | — |
| Reactant | HCID 178478990 | HCID 178478990 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 22731342 | HCID 22731342 | — |
Reaction Steps
Following General Procedure K and using 5-bromo-3,3-dimethyl-2,3-dihydrobenzofuran-7-carbaldehyde (Intermediate 30, 0.765 g, 3 mmol), 10 mL of anhydrous diethyl ether, and a 2M solution of cyclohexyl magnesium chloride solution in ether (3 mL, 6 mmol) followed by flash column chromatography using 10% ethyl acetate in hexane, the title compound was obtained (0.62 g, 61%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720423B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-579feeb74c05425a9cb24a8acfc2e5b5 |
| Source note | uspto-grants-2004_04 |