HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 3,3-Dimethyl-7-hexyl-2,3-dihydro-benzofuran-5-boronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Trimethyl borate | HCID 8470 | — |
| Reactant | 5-Bromo-3,3-dimethyl-7-hexyl-2,3-dihydro-benzofuran | HCID 22731286 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Solvent | Pentane | HCID 8003 | — |
| Product | 3,3-Dimethyl-7-hexyl-2,3-dihydro-benzofuran-5-boronic acid | HCID 22731339 | — |
Reaction Steps
Following General Procedure A and using 5-bromo-7-hexyl-3,3-dimethyl-2,3-dihydro-benzofuran (Intermediate 53, 1.32 g, 4.26 mmol), anhydrous tetrahydrofuran, 1.7M solution of t-butyllithium in n-pentane and trimethyl borate, the title compound was obtained as a foam that was used as such for the next step without purification and characterization.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720423B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-af32fb3b83e6458a91c9eadca3b0296f |
| Source note | uspto-grants-2004_04 |