Ethanol → HCID 10251354, compound

Participants

Reaction Steps

Following General Procedure H and using 5-{(1S, 2S)-2-[7-(2,6-dimethyl-phenyl)-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl]-2-methyl-cyclopropyl}-3-methyl-penta-2E,4 Edienoic acid ethyl ester (Compound 23, 0.109 g, 0.24 mmol), ethanol (15 mL), and 5M aqueous sodium hydroxide (1 mL) followed by flash column chromatography using 25% in hexane as the eluent, and reverse phase HPLC, the title compound was obtained (0.049 g, 50%) as a white solid.

Provenance & Evidence