Ethanol → HCID 9978476, compound

Participants

Reaction Steps

Following General Procedure H and using 5-[(1S, 2S)-2-(3,3-dimethyl-7-o-tolyl-2,3-dihydro-benzofuran-5-yl)-2-methyl-cyclopropyl]-3-methyl-penta-2E,4E-dienoic acid ethyl ester (Compound 25, 0.096 g, 0.22 mmol), ethanol (20 mL), and 5M aqueous sodium hydroxide (5 mL) followed by preparative reverse phase HPLC using 10% water in acetonitrile as the mobile phase, the title compound was obtained (0.044 g, 45%) as a white solid.

Provenance & Evidence