HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 1-Bromo-2-heptyl-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | 1-(2-Bromo-phenyl)-heptan-1-ol | HCID 22731273 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Bromo-2-heptyl-benzene | HCID 22731318 | — |
Reaction Steps
Following General Procedure J and using 1-(2-Bromo-phenyl)-heptan-1-ol (1.86 g, 6.9 mmol), anhydrous dichloromethane (5 mL), trifluoroacetic acid (2.5 mL, 32.5 mmol) and triethyl silane (5 mL, 31 mmol) followed by flash column chromatography, the title compound was obtained (0.4 g, 23%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720423B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-2704e5e660b648e283de9f673fb2f4a1 |
| Source note | uspto-grants-2004_04 |