Methanol → HCID 69887938, compound

Participants

Reaction Steps

Following General Procedure B and using 3,3-dimethyl-2,3-dihydro-benzofuran-5-boronic acid (Intermediate 3, crude, 10 mmol), 3-iodo-prop-2 (Z)-ene-ol (Intermediate 69, 1.35 g, 7.29 mmol), methanol (20 mL), toluene (40 mL), water (10 mL), sodium carbonate (1.58 g, 15 mmol) and tetrakis(triphenylphosphine)palladium(0)(100 mg), followed by flash column chromatography over silica gel (230-400 mesh) using 15% ethyl acetate in hexane as the eluent the title compound was obtained (0.16 g, 8%).

Provenance & Evidence