Methanol → HCID 10002596, compound

Participants

Reaction Steps

Following General Procedure H and using (E)-3-((E)-2-{(1S,2S)-2-[7-(3-hydroxy-heptyl)-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl]-2-methyl-cyclopropyl}-vinyl)-but-2-enoic acid ethyl ester (Compound 37, 0.007 g, 0.015 mmol), methanol (1.5 mL), tetrahydrofuran (1.5 mL) and 1M aqueous sodium hydroxide (0.5 mL) followed by preparative reverse phase HPLC using 10% water in acetonitrile as the eluent, the title compound was obtained (0.0044 g, 67%).

Provenance & Evidence