Cumene → 2-Phenyl-2-propanol

Participants

Reaction Steps

In a round-bottom flask fitted with superposed reflux condenser, 30 mmol of cumene are admixed at a temperature of 125° C. with 0.3 mmol of N-hydroxyphthalimide and 0.3 mmol of cobalt(II) acetate. The reaction mixture is stirred at the specified temperature under an oxygen atmosphere of 1 bar for 8 hours. The target product is not formed, but instead acetophenone with a selectivity of 58.7%, 2-phenyl-2-propanol (13.1%) and phenol (10.4%) are obtained at a cumene conversion of 49.3%.

Provenance & Evidence