Cyclohexane, (ethenyloxy)- → HCID 12994198, Verbindung

HRID 2085625Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2085625
C1(C)C=CC(S([O-])(=O)=O)=CC=1.[NH+]1C=CC=CC=1.[C:18]([O:23][CH2:24][CH:25]([CH3:27])[CH3:26])(=[O:22])[C@@H:19]([CH3:21])[OH:20].[CH:28]([O:30][CH:31]1[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1)=[CH2:29]>C(OCC)(=O)C>[CH:31]1([O:30][CH:28]([O:20][C@H:19]([CH3:21])[C:18]([O:23][CH2:24][CH:25]([CH3:27])[CH3:26])=[O:22])[CH3:29])[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1

Komponenten

5

Edukt 3

HCID 75129Cyclohexane, (ethenyloxy)-HCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)HCID 104869892-Methylpropyl-(R)-2-hydroxypropanoate

Produkt 1

HCID 12994198HCID 12994198, VerbindungAusbeute 99,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

A catalytic amount of pyridinium para-toluenesulfonate was added to 29.2 g (0.2 mole) of isobutyl (R)-(+)-lactate and 28.0 g (0.22 mole) of cyclohexyl vinyl ether. The resulting mixture was stirred at room temperature for 4 hours to give rise to a reaction. Thereto was added 100 ml of ethyl acetate, followed by washing with 100 ml of a saturated aqueous sodium hydrogen carbonate solution, 40 ml of water and 40 ml of a saturated aqueous sodium chloride solution in this order. The washed material was dried over anhydrous sodium sulfate and then subjected to vacuum distillation to remove the solvent, whereby was obtained 54.2 g (yield: 99.4%) of an oily title compound (diastereomixture).

Aufarbeitung

  1. customto give rise
  2. customto a reaction
  3. washby washing with 100 ml of a saturated aqueous sodium hydrogen carbonate solution, 40 ml of water and 40 ml of a saturated aqueous sodium chloride solution in this order
  4. dry with materialThe washed material was dried over anhydrous sodium sulfate
  5. distillationsubjected to vacuum distillation
  6. customto remove the solvent

Quellen und Nachweise

ORD-Eintrag
ord-f3ffd66015e743289eaaf4ea9e62d370
Quelldatensatz
uspto-grants-2004_04
Patentnummer
US06720463B1

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