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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2085643Generated: October 25, 2026

3-Mercaptopropanol → 2-Chloro-5-[2-(3-hydroxypropylthio)ethoxy]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide

https://huagongshe.com/reaction/2085643

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MercaptopropanolHCID 88211—
Reactant2-chloro-5-(2-chloroethoxy)-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamideHCID 22731484—
Product2-Chloro-5-[2-(3-hydroxypropylthio)ethoxy]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamideHCID 10181596—

Reaction Steps

Prepared according to the method of Example 10 using 2-chloro-5-(2-chloroethoxy)-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide (Example 11a, 0.34 g) and 3-mercaptopropan-1-ol (0.25 ml) to give the title compound (0.4 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06720452B2
Source datasetuspto-grants-2004_04
ORD IDord-4f4afe1c270f4eb486e85f84edb6457b
Source noteuspto-grants-2004_04