Benzocaine → HCID 22730760, compound

HRID 2085756Notes

Reaction equation

HRID 2085756 reaction equation
[CH2:1]1[CH2:5][C:4]2([CH2:12][C:10](=[O:11])[O:9][C:7](=O)[CH2:6]2)[CH2:3][CH2:2]1.[NH2:13][C:14]1[CH:24]=[CH:23][C:17]([C:18]([O:20][CH2:21]C)=[O:19])=[CH:16][CH:15]=1.CC1(C)CC(=O)OC(=O)C1>>[O:11]=[C:10]1[N:13]([C:14]2[CH:15]=[CH:16][C:17]([C:18]([O:20][CH3:21])=[O:19])=[CH:23][CH:24]=2)[C:7](=[O:9])[CH2:6][C:4]2([CH2:3][CH2:2][CH2:1][CH2:5]2)[CH2:12]1

Participants

4

Reactant 3

HCID 2337BenzocaineHCID 778133,3-Dimethylglutaric anhydrideHCID 79743Cyclopentane-1,1-diacetic anhydride

Product 1

HCID 22730760HCID 22730760, compound

Procedure

The desired product was prepared by substituting methyl 4-aminobenzoate and 3,3-tetramethyleneglutaric anhydride for ethyl 4-aminobenzoate and 3,3-dimethylglutaric anhydride, respectively, in Example 119A. MS (DCI) m/e 302 (M+H)+.

Sources & evidence

ORD record
ord-15afaa43714144ccbbe8b52fb6ce846e
Source dataset
uspto-grants-2004_04
Patent number
US06720338B2

Reaction notes

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