4-Fluorophenylboronic acid → HCID 22730747, compound

HRID 2085759Notes

Reaction equation

HRID 2085759 reaction equation
[CH2:1]([O:3][C:4](=[O:13])[C:5]1[CH:10]=[CH:9][C:8](Br)=[C:7]([CH3:12])[CH:6]=1)[CH3:2].[F:14][C:15]1[CH:20]=[CH:19][C:18](B(O)O)=[CH:17][CH:16]=1>>[F:14][C:15]1[CH:20]=[CH:19][C:18]([C:8]2[CH:9]=[CH:10][C:5]([C:4]([O:3][CH2:1][CH3:2])=[O:13])=[CH:6][C:7]=2[CH3:12])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 2856454-Fluorophenylboronic acidHCID 21729626Ethyl 4-bromo-3-methylbenzoate

Product 1

HCID 22730747HCID 22730747, compound

Procedure

The desired product was prepared by substituting 4-bromo-3-methylbenzoic acid ethyl ester and 4-fluorophenylboronic acid for Example 186B and Example 186A, respectively, in Example 186C.

Sources & evidence

ORD record
ord-b6f3a226201a4aa79a76c929fff1d37c
Source dataset
uspto-grants-2004_04
Patent number
US06720338B2

Reaction notes

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