HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 22730308, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Isobutylene | HCID 8255 | — |
| Reactant | 5-Bromo-benzo(b)thiophene-2-carboxylic acid | HCID 737737 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22730308 | HCID 22730308 | — |
Reaction Steps
A mixture of Example 274B and concentrated H2SO4 (0.5 mL) in dichloromethane (100 mL) saturated with isobutylene at room temperature was stirred for 4 hours and concentrated. The concentrate was purified by flash column chromatography on silica gel with 2% ethyl acetate/hexanes to provide the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720338B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-1616f9e58c3f4ab49455f8f7407ff589 |
| Source note | uspto-grants-2004_04 |