HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → Methyl 4-(4-oxocyclohex-1-en-1-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Methyl 4-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)benzoate | HCID 22730331 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Methyl 4-(4-oxocyclohex-1-en-1-yl)benzoate | HCID 22730167 | — |
Reaction Steps
A solution of Example 420B (2.2 g) and p-toluenesulfonic acid (100 mg) in acetone (10 mL) was heated to reflux for 10 hours, filtered through a pad of silica gel (20 g), and concentrated to provide the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720338B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-93306aa38c524d7fba5aff3541cb9136 |
| Source note | uspto-grants-2004_04 |