Sulfur → HCID 22727488, compound

Participants

Reaction Conditions

Reaction Steps

1.79 g (8.28 mmol) of yellow mercuric oxide and 27 mg of flowers of sulfur were added to 1.4 g (4.14 mmol) of 3-(2-aminophenyl)-1-(4-tert-butyloxycarbonylaminobutyl)thiourea (Example 23b) in 30 ml of ethanol and the reaction mixture was heated at 50-55° C. for 3 h. The solid was filtered off with suction and washed with ethanol. The filtrate was concentrated and the product was chromatographed through silica gel (DCM:methanol 9:5, then 9:1). Yield: 43%. MS (ES+): m/e=305.2 ( (M+H)+, 100%).

Provenance & Evidence