HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Amino-2-(dimethylamino)isonicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-(N,N-Dimethylamino)-5-(2,2-dimethylpropionamido)-pyridine-4-carboxylic acid | HCID 22727450 | — |
| Product | 5-Amino-2-(dimethylamino)isonicotinic acid | HCID 22727430 | 98.8% |
Reaction Steps
2-(N,N-Dimethylamino)-5-(2,2-dimethylpropionamido)-pyridine-4-carboxylic acid (0.8 g) was treated with 5N HCl at reflux for 5 hours. The mixture was allowed to cool and evaporated to dryness to give the title compound (0.54 g); δH [2H6]DMSO 8.15(1H,s), 7.35(2H,bs), 6.70(1H,s), 3.10(6H,s), m/z (M+1+) 182.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723726B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-604f71be9259408d96c59334585c156e |
| Source note | uspto-grants-2004_04 |