Sodium borohydride → HCID 22726938, compound

HRID 2085977Notes

Reaction equation

[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][NH:11][C:12]1[S:13][C:14]([S:29]C#N)=[C:15]([CH2:17][S:18][CH2:19][CH2:20][NH:21][C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[N:16]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[BH4-].[Na+]>>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][NH:11][C:12]1[S:13][C:14]([SH:29])=[C:15]([CH2:17][S:18][CH2:19][CH2:20][NH:21][C:22]([O:24][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:23])[N:16]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 22726875HCID 22726875, compound

Product 1

HCID 22726938HCID 22726938, compound

Procedure

2-(2-t-butoxycarbonylaminoethylamino)-4-(2-t-butoxycarbonylaminoethylthiomethyl)-5-thiocyanato-1,3-thiazole was reduced with sodium borohydride in a manner similar to that described in Example 44 to produce title compound.

Sources & evidence

ORD record: ord-8c299ac6bec7402e9adba2bbc2fe4e70
Source dataset: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06723716B1

Reaction notes

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